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Generic Name: hydromorphone (injection) (hy dro MOR fone)
Brand Names: Dilaudid, Dilaudid-HP

What is Dilaudid (hydromorphone (injection))?

Hydromorphone is in a group of drugs called narcotic pain relievers. It is similar to morphine.

Hydromorphone injection is used to treat moderate to severe pain.

Hydromorphone injection may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Dilaudid (hydromorphone (injection))?

You should not receive hydromorphone injection unless you are already being treated with a similar opioid pain medicine and your body is tolerant to it. Talk with your doctor if you are not sure you are opioid-tolerant.

What should I discuss with my healthcare provider before receiving Dilaudid (hydromorphone (injection))?

Before receiving hydromorphone, tell your doctor if you are allergic to any drugs, or if you have:

• asthma, COPD, sleep apnea, or other breathing disorders;

• liver or kidney disease;

• underactive thyroid;

• curvature of the spine;

• a history of head injury or brain tumor;

• epilepsy or other seizure disorder;

• low blood pressure;

• gallbladder disease;

• Addison's disease or other adrenal gland disorders;

• enlarged prostate, urination problems;

• mental illness; or

• a history of drug or alcohol addiction.

You should not use hydromorphone injection unless you are already being treated with a similar opioid pain medicine and your body is tolerant to it. Opioid medicines include fentanyl (Actiq, Duragesic), methadone (Methadose, Dolophine), morphine (Kadian, MS Contin, Oramorph, and others), oxycodone (Oxycontin), oxymorphone (Opana), and any other forms of hydromorphone. Talk with your doctor if you are not sure you are opioid-tolerant.

How is hydromorphone injection used?

This medication is given as an injection through a needle placed under your skin or into a muscle. You will receive this injection in a clinic or hospital setting.

Tell your doctor if the medicine seems to stop working as well in relieving your pain.

If you need to have any type of surgery, tell the surgeon ahead of time that you are using hydromorphone. You may need to stop using the medicine for a short time.

What happens if I miss a dose?

Since hydromorphone is usually given by a healthcare provider, it is not likely that you will miss a dose.

What happens if I overdose?

Overdose symptoms may include extreme drowsiness, pinpoint pupils, confusion, cold and clammy skin, weak pulse, shallow breathing, fainting, or breathing that stops.

What should I avoid while receiving Dilaudid (hydromorphone (injection))?

Dilaudid (hydromorphone (injection)) side effects

• shallow breathing, slow heartbeat;

• seizure (convulsions);

• cold, clammy skin;

• confusion;

• severe weakness or dizziness; or

• feeling light-headed, fainting.

Less serious side effects are more likely to occur, such as:

• constipation;

• warmth, tingling, or redness under your skin;

• nausea, vomiting, diarrhea, loss of appetite;

• dizziness, headache;

• pain or tenderness where the injection was given;

• dry mouth;

• sweating;

• itching; or

• sleep problems (insomnia).

This list is not complete and other side effects may occur. Tell your doctor about any unusual or bothersome side effect.

What other drugs will affect Dilaudid (hydromorphone (injection))?

Before receiving hydromorphone injection, tell your doctor if you are using pentazocine (Talwin), nalbuphine (Nubain), butorphanol (Stadol), or buprenorphine (Buprenex, Subutex). If you are using any of these drugs, you may not be able to use hydromorphone, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can interact with hydromorphone. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about hydromorphone injection.

• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.