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Desmopressin is used for:

Short-term treatment of nighttime bedwetting. It is also used to manage temporary excessive thirst and urination in patients with head trauma or who have had surgery in certain areas of the brain, or to control diabetes insipidus. It may also be used for other conditions as determined by your doctor.

Desmopressin is an antidiuretic hormone. It works by causing the kidneys to retain water, which decreases the amount of urine produced.

Do NOT use Desmopressin if:

• you are allergic to any ingredient in Desmopressin

Contact your doctor or health care provider right away if any of these apply to you.

Before using Desmopressin :

Some medical conditions may interact with Desmopressin . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have moderate to severe kidney problems

Some MEDICINES MAY INTERACT with Desmopressin . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Loperamide because it increases the actions and side effects of Desmopressin and could increase the possibility of water intoxication (symptoms include headache, nausea, vomiting, or seizures)

This may not be a complete list of all interactions that may occur. Ask your health care provider if Desmopressin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Desmopressin :

Use Desmopressin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Carefully read and follow the patient instructions for use of the spray pump before using Desmopressin .
• Desmopressin is to be used only in the nose.
• The pump must be primed before the first use. To prime the pump, press down 4 times.
• Throw the bottle away after 50 sprays. Do not try to transfer the remaining medicine to another bottle.
• If you miss a dose of Desmopressin , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Desmopressin .

Important safety information:

• Follow the fluid intake instructions given to you by your health care provider very carefully. Serious side effects may occur if you drink too much liquid while taking Desmopressin , especially in children and the elderly.
• Do not use more of Desmopressin or use it for longer than recommended because serious side effects may occur.
• LAB TESTS, including urine volume, may be performed to monitor your progress. Be sure to keep all doctor and lab appointments.
• ELDERLY patients should carefully follow limited fluid intake according to their health care provider's instructions.
• Desmopressin is not recommended for use in CHILDREN younger than 3 months of age or CHILDREN with nighttime bedwetting younger than 5 years of age. Safety and effectiveness have not been confirmed in these patients.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Desmopressin during pregnancy. It is unknown if Desmopressin is excreted in breast milk. If you are or will be breast-feeding while you are using Desmopressin , check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Desmopressin :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Chills; cough; dizziness; flushing; headache; nasal congestion; nausea; nosebleed; nostril pain; red or swollen eyes; runny nose; sore throat; stomach cramps or disorder; upper respiratory tract infection; watery eyes; weakness.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; conjunctivitis (pink eye); ongoing headache; prolonged nausea or vomiting; scarring or swelling of the nose; seizures; unusual tiredness; unusual weight gain.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include facial flushing; fluid retention (decreased urination, ongoing headache, prolonged nausea or vomiting, seizures); irritation of the tissue in the nose and mouth; shortness of breath; stomach pain. Desmopressin may be harmful if swallowed.

Store Desmopressin in the refrigerator between 36 and 46 degrees F (2 and 8 degrees C). When traveling, Desmopressin may be kept out of the refrigerator for up to 3 weeks if stored at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Store the bottle in an upright position. Keep Desmopressin out of the reach of children and away from pets.

General information:

• If you have any questions about Desmopressin , please talk with your doctor, pharmacist, or other health care provider.
• Desmopressin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Desmopressin . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.