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Generic Name: chlordiazepoxide and clidinium (klor dye az e POX ide and kli DI nee um)
Brand Names: Chlordinium, Clindex, Librax

What is chlordiazepoxide and clidinium?

Chlordiazepoxide is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Chlordiazepoxide affects chemicals in the brain that may become unbalanced and cause anxiety.

Clidinium reduces stomach acid and decreases intestinal spasms.

The combination of chlordiazepoxide and clidinium is used to treat stomach ulcers, irritable bowel syndrome, and intestinal infections.

Chlordiazepoxide and clidinium may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about chlordiazepoxide and clidinium?

Before taking chlordiazepoxide and clidinium, tell your doctor if you have any breathing problems, glaucoma, porphyria, kidney or liver disease, or a history of depression, suicidal thoughts, or addiction to drugs or alcohol.

Avoid using other medicines that make you sleepy. They can add to sleepiness caused by chlordiazepoxide and clidinium.

What should I discuss with my health care provider before taking chlordiazepoxide and clidinium?

Do not take chlordiazepoxide and clidinium if you have:

• glaucoma;

• an enlarged prostate;

• a bladder obstruction; or

• problems with urination.

Before taking chlordiazepoxide, tell your doctor if you are allergic to any drugs, or if you have:

• asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems;

• myasthenia gravis;

• ulcerative colitis, or a blockage in your intestines;

• kidney or liver disease;

• a history of depression or suicidal thoughts or behavior; or

• a history of drug or alcohol addiction.

If you have any of these conditions, you may not be able to use chlordiazepoxide, or you may need a dosage adjustment or special tests during treatment.

How should I take chlordiazepoxide and clidinium?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Chlordiazepoxide and clidinium is usually taken before meals and at bedtime. Follow your doctor's instructions.

Keep track of how many pills have been used from each new bottle of this medicine. Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Symptoms of a chlordiazepoxide and clidnium overdose may include extreme drowsiness, dry mouth, blurred vision, confusion, muscle weakness, slow or shallow breathing, feeling light-headed, or fainting.

What should I avoid while taking chlordiazepoxide and clidinium??

Avoid using other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). They can increase some of the side effects of chlordiazepoxide and clidinium.

Chlordiazepoxide and clidinium side effects

• confusion;

• depressed mood, thoughts of suicide or hurting yourself;

• restless muscle movements in your eyes, tongue, jaw, or neck;

• hyperactivity, agitation, hostility;

• hallucinations;

• jaundice (yellowing of the skin or eyes); or

• urinating less than usual or not at all.

Less serious side effects are more likely to occur, such as:

• drowsiness, tiredness;

• swelling;

• skin rash;

• blurred vision;

• dry mouth;

• nausea, vomiting, constipation; or

• irregular menstrual periods.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect chlordiazepoxide and clidinium?

Before taking chlordiazepoxide and clidnium, tell your doctor if you are using any of the following drugs:

• a barbiturate such as amobarbital (Amytal), butabarbital (Butisol), mephobarbital (Mebaral), secobarbital (Seconal), or phenobarbital (Luminal, Solfoton);

• a blood thinner such as warfarin (Coumadin);

• an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate);

• medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), haloperidol (Haldol), mesoridazine (Serentil), pimozide (Orap), or thioridazine (Mellaril);

• narcotic medications such as butorphanol (Stadol), codeine, hydrocodone (Lortab, Vicodin), levorphanol (Levo-Dromoran), meperidine (Demerol), methadone (Dolophine, Methadose), morphine (Kadian, MS Contin, Oramorph), naloxone (Narcan), oxycodone (OxyContin), propoxyphene (Darvon, Darvocet); or

• antidepressants such as amitriptyline (Elavil, Etrafon), amoxapine (Ascendin), citalopram (Celexa), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), protriptyline (Vivactil), sertraline (Zoloft), or trimipramine (Surmontil).

If you are using any of these drugs, you may not be able to use chlordiazepoxide and clidinium, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect chlordiazepoxide and clidinium. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

• Your pharmacist has information about chlordiazepoxide and clidinium written for health professionals that you may read.

What does my medication look like?

Chlordiazepoxide and clidinium is available with a prescription under the brand names Chlordinium, Clindex, and Librax. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.