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Generic name: Olsalazine sodium
Brand names: Dipentum

Why is Olsalazine sodium prescribed?

Dipentum is an anti-inflammatory drug used to maintain long-term freedom from symptoms of ulcerative colitis (chronic inflammation and ulceration of the large intestine and rectum). It is prescribed for people who cannot take sulfasalazine (Azulfidine).

Most important fact about Olsalazine sodium

If you have kidney disease, Dipentum could cause further damage. You'll need regular checks on your kidney function, so be sure to keep all regular appointments with your doctor.

How should you take Olsalazine sodium?

Take Dipentum for as long as your doctor has directed, even if you feel better.

Take Dipentum with food.

--If you miss a dose...

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.

--Storage instructions...

Store at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Dipentum.

• More common side effects may include:
  Diarrhea or loose stools

Rare cases of hepatitis have been reported in people taking Dipentum. Symptoms may include aching muscles, chills, fever, headache, joint pain, loss of appetite, vomiting, and yellowish skin.

Why should Olsalazine sodium not be prescribed?

You should not be using Dipentum if you are allergic to salicylates such as aspirin.

Special warnings about Olsalazine sodium

If diarrhea occurs, contact your doctor.

Possible food and drug interactions when taking Olsalazine sodium

If Dipentum is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Dipentum with warfarin (Coumadin).

Special information if you are pregnant or breastfeeding

The effects of Dipentum in pregnancy have not been adequately studied. Pregnant women should use Dipentum only if the possible gains warrant the possible risks to the unborn child. Women who breastfeed an infant should use Dipentum cautiously, because it is not known whether Olsalazine sodium appears in breast milk and what effect it might have on a nursing infant.

Recommended dosage

ADULTS

The usual dose is a total of 1 gram per day, divided into 2 equal doses.

CHILDREN

Safety and effectiveness have not been established in children.

Overdosage

There have been no reports of Dipentum overdose. However, should you suspect one, seek medical help immediately.