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Meclizine is used for:

Preventing and treating nausea, vomiting, and dizziness associated with motion sickness. It is also used for vertigo (or dizziness) caused by certain inner ear problems. It may also be used for other conditions as determined by your doctor.

Meclizine is an anticholinergic. It works by blocking a chemical messenger in the brain, which helps to reduce or prevent vomiting.

Do NOT use Meclizine if:

• you are allergic to any ingredient in Meclizine
• you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Meclizine :

Some medical conditions may interact with Meclizine . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• you have asthma; chronic obstructive pulmonary disease (COPD); chronic bronchitis or emphysema; blockage of the stomach, intestine, or urinary tract;enlargement of the prostate; or glaucoma

Some MEDICINES MAY INTERACT with Meclizine . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Sodium oxybate ( GHB) because an increase in sleep duration and a decrease in the ability to breathe are likely to occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Meclizine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Meclizine :

Use Meclizine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Meclizine by mouth with or without food.
• For prevention of motion sickness, take Meclizine at least 1 hour before activity or travel.
• Use Meclizine exactly as directed on the package, unless instructed differently by your doctor. If you are taking Meclizine without a prescription, follow any warnings and precautions on the label.
• If you miss a dose of Meclizine and are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Meclizine .

Important safety information:

• Meclizine may cause drowsiness or blurred vision. This effect may be worse if you take it with alcohol or certain medicines. Use Meclizine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Meclizine ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
• This product may contain tartrazine dye (FD&C Yellow No. 5). This may cause an allergic reaction in some patients. If you have ever had an allergic reaction to tartrazine, ask your pharmacist if your product has tartrazine in it.
• Meclizine should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Meclizine while you are pregnant. It is not known if Meclizine is found in breast milk. If you are or will be breast-feeding while you use Meclizine , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Meclizine :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Drowsiness; dry mouth.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include drowsiness; hallucinations; seizures; unusual excitability; very slow or shallow breathing.

Store Meclizine at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Meclizine out of the reach of children and away from pets.

General information:

• If you have any questions about Meclizine , please talk with your doctor, pharmacist, or other health care provider.
• Meclizine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Meclizine . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.