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L-Methylfolate/B12/B6/B2 is used for:

Managing hyperhomocysteinemia or to supplement the diet. It may also be used to treat other conditions as determined by your doctor.

L-Methylfolate/B12/B6/B2 is a vitamin combination. It provides nutritional supplementation for certain nutritional requirements.

Do NOT use L-Methylfolate/B12/B6/B2 if:

• you are allergic to any ingredient in L-Methylfolate/B12/B6/B2

Contact your doctor or health care provider right away if any of these apply to you.

Before using L-Methylfolate/B12/B6/B2 :

Some medical conditions may interact with L-Methylfolate/B12/B6/B2 . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, plan to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have Leber hereditary optic atrophy (an eye disease) or megaloblastic anemia

Some MEDICINES MAY INTERACT with L-Methylfolate/B12/B6/B2 . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Fluorouracil because its actions and side effects may be increased
• Hydantoins (eg, phenytoin) because the effectiveness of these medicines may be decreased, leading to increased seizure frequency

This may not be a complete list of all interactions that may occur. Ask your health care provider if L-Methylfolate/B12/B6/B2 may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use L-Methylfolate/B12/B6/B2 :

Use L-Methylfolate/B12/B6/B2 as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• L-Methylfolate/B12/B6/B2 may be taken with or without food.
• If you miss taking a dose of L-Methylfolate/B12/B6/B2 for 1 or more days, there is no cause for concern. If your doctor recommended that you take it, try to remember your dose every day.

Ask your health care provider any questions you may have about how to use L-Methylfolate/B12/B6/B2 .

Important safety information:

• Do not take large doses of vitamins unless directed to by your doctor.
• Check any other vitamin products you may be taking for folic acid content. Tell your doctor or pharmacist if any other medicine that you take contains folic acid.
• PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using L-Methylfolate/B12/B6/B2 during pregnancy. It is unknown if L-Methylfolate/B12/B6/B2 is excreted in breast milk. If you are or will be breast-feeding while you are using L-Methylfolate/B12/B6/B2 , check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of L-Methylfolate/B12/B6/B2 :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Drowsiness; feeling of swelling of the entire body; mild diarrhea; numbness or tingling.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Store L-Methylfolate/B12/B6/B2 at room temperature between 59 and 86 degrees F (15 and 30 degrees C) away from heat, moisture, and light. Do not store in the bathroom. Keep L-Methylfolate/B12/B6/B2 out of the reach of children and away from pets.

General information:

• If you have any questions about L-Methylfolate/B12/B6/B2 , please talk with your doctor, pharmacist, or other health care provider.
• L-Methylfolate/B12/B6/B2 is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about L-Methylfolate/B12/B6/B2 . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.