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Generic Name: immune globulin (subcutaneous) (im MYOON GLOB yoo lin)
Brand Names: Vivaglobin

What is immune globulin?

Immune globulin subcutaneous is a sterilized solution made from human plasma. It contains the antibodies to help your body protect itself against infection from various diseases.

Immune globulin is used to treat primary immune deficiency.

Immune globulin may also be used for purposes other than those listed here.

What is the most important information I should know about immune globulin?

Use this medication exactly as it was prescribed for you. Do not use it in larger doses or for longer than recommended by your doctor.

Before using this medication, tell your doctor if you are pregnant or breast-feeding.

If you miss a dose, use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not use extra medicine to make up the missed dose.

There may be other drugs that can affect immune globulin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Less serious side effects are more likely, and you may have none at all. Talk to your doctor about any side effect that seems unusual or is especially bothersome.

Immune globulin is made from human plasma (part of the blood) and may contain viruses and other infectious agents that can cause disease. Although immune globulin is screened, tested, and treated to reduce the risk of it containing anything that could cause disease, there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.

What should I discuss with my health care provider before taking immune globulin?

• an allergy to human immune globulin;

• immune globulin A (IgA) deficiency.

If you have any of these conditions, you may not be able to receive immune globulin, or you may require a dosage adjustment or special tests during treatment.

If you have already started treatment with immune globulin, tell your doctor if it has been 8 weeks or longer since your last dose.

Using immune globulin may affect the results if you have certain medical tests. Tell any doctor who treats you that you are using immune globulin.

How should I take immune globulin?

Use immune globulin subcutaneous exactly as it was prescribed for you. Do not use it in larger doses or for longer than recommended by your doctor.

Immune globulin subcutaneous is given as an injection under the skin, usually into the stomach, hip, thigh, or upper arm. You may also receive several injections at one time using a pump that sends the medicine through tubes connected to needles placed just under the skin at different locations on your body.

This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Your doctor, nurse, or pharmacist will give you specific instructions on how and where to inject this medicine. Do not give yourself an injection if you do not understand these instructions. Call your doctor, nurse, or pharmacist for help with injection instructions.

Immune globulin subcutaneous must never be injected into a blood vessel or vein. Before injecting the medicine, you will need to place the needle in your skin and test to make sure it is placed only in the skin and not in a vein. To do this, gently pull back on the plunger of the syringe that is connected to the needle or tubing. If blood flows back into the syringe, remove the needle and tubing and throw them away. Using a new needle and syringe or tubing, place the needle in a new location and do another blood flowback test to make sure the needle is not in a vein.

Do not draw your immune globulin dose into a syringe until you are ready to give yourself an injection. Do not use the medication if it has changed colors or has any particles in it. Call your doctor for a new prescription. Throw away any unused medicine that is left over after injecting your dose.

Use each needle and syringe only one time. With your medicine you will receive a puncture-proof container for used needles and syringes. If you do not receive a container, ask your pharmacist for one. Keep this container out of the reach of children and pets. Your pharmacist can tell you how to properly dispose of the container.

If you use this medication at home, keep a diary of the days and times you used the medication and where you injected it on your body.

What happens if I miss a dose?

Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

What should I avoid while taking immune globulin?

There are no restrictions on food, beverages, or activity while using immune globulin unless your doctor tells you otherwise.

Immune globulin side effects

• fever, chills, shaking, nausea, vomiting;

• fast heartbeat; or

• nervousness.

Other less serious side effects are more likely to occur, such as:

• redness, itching, and swelling of skin where the shots are given;

• headache;

• mild itching or skin rash;

• upset stomach;

• sore throat; or

• diarrhea.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect immune globulin?

Where can I get more information?

• Your pharmacist has more information about immune globulin subcutaneous written for health professionals that you may read.

What does my medication look like?

Immune globulin subcutaneous is available with a prescription under the brand name Vivaglobin. Other brand or generic forms may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.