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Hyoscyamine Elixir

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Generic Name: Hyoscyamine Elixir (HYE-oh-SYE-a-meen)
Brand Name: Examples include Levsin and Spasdel

Hyoscyamine Elixir is used for:

Treating certain stomach, intestinal, and bladder conditions, including spasms. It is used to control stomach secretions and cramps. It is used to relieve the symptoms of colic, runny nose, and Parkinson-like problems. It is used to treat excessive sweating or saliva production. It may also be used for other conditions as determined by your doctor.

Hyoscyamine Elixir is an anticholinergic agent. It works by decreasing the motion of muscles in the stomach, intestines, and bladder. It also decreases the production of stomach acid.

Do NOT use Hyoscyamine Elixir if:

  • you are allergic to any ingredient in Hyoscyamine Elixir
  • you have severe esophagus problems (eg, irritation, narrowing); a blockage of the stomach, bowel, or bladder; bowel motility problems; or severe bowel problems (eg, severe ulcerative colitis, toxic megacolon)
  • you have glaucoma, myasthenia gravis, or heart problems caused by severe bleeding

Contact your doctor or health care provider right away if any of these apply to you.

Before using Hyoscyamine Elixir:

Some medical conditions may interact with Hyoscyamine Elixir. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have nerve problems, prostate problems, stomach or bowel problems, heart or blood vessel problems (eg, fast or irregular heartbeat, heart failure, coronary heart disease), hiatal hernia, kidney problems, an overactive thyroid, high blood pressure, urinary problems, paralysis, or brain damage, or if you are at risk for glaucoma
  • if you have diarrhea or fever, have been very ill, or are in poor health

Some MEDICINES MAY INTERACT with Hyoscyamine Elixir. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Amantadine, antihistamines (eg, diphenhydramine), haloperidol, monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), other anticholinergics (eg, scopolamine), phenothiazines (eg, thioridazine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Hyoscyamine Elixir's side effects
  • Narcotic pain medicines (eg, codeine) or potassium chloride because the risk of their side effects may be increased by Hyoscyamine Elixir
  • Metoclopramide because its effectiveness may be decreased by Hyoscyamine Elixir

This may not be a complete list of all interactions that may occur. Ask your health care provider if Hyoscyamine Elixir may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Hyoscyamine Elixir:

Use Hyoscyamine Elixir as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Hyoscyamine Elixir is usually taken 30 to 60 minutes before a meal. Follow your doctor's specific instructions for taking Hyoscyamine Elixir.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • If you also take antacids, take Hyoscyamine Elixir before meals and the antacid after meals, unless directed otherwise by your doctor.
  • If you miss a dose of this medicine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Hyoscyamine Elixir.

Important safety information:

  • Hyoscyamine Elixir may cause drowsiness, dizziness, blurred vision, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Hyoscyamine Elixir with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Hyoscyamine Elixir will add to the effects of alcohol and other medicines that may cause drowsiness (eg, sleep aids, muscle relaxers). Ask your pharmacist if you have any questions about which medicines may cause drowsiness.
  • Do not become overheated in hot weather or while you are being active; heatstroke may occur.
  • Drink plenty of fluids, maintain good oral hygiene, and suck on sugarless hard candy to relieve dry mouth.
  • Proper dental care is important while you are taking Hyoscyamine Elixir. Brush and floss your teeth and visit the dentist regularly.
  • Hyoscyamine Elixir may make your eyes more sensitive to sunlight. It may help to wear sunglasses.
  • Use Hyoscyamine Elixir with caution in the ELDERLY; they may be more sensitive to its effects, especially constipation, trouble urinating, drowsiness, agitation, confusion, or excitement.
  • Caution is advised when using Hyoscyamine Elixir in CHILDREN; they may be more sensitive to its effects.
  • Hyoscyamine Elixir should be used with extreme caution in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: It is not known if Hyoscyamine Elixir can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Hyoscyamine Elixir while you are pregnant. Hyoscyamine Elixir is found in breast milk. If you are or will be breast-feeding while taking Hyoscyamine Elixir, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Hyoscyamine Elixir:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Bloated feeling; blurred vision; constipation; decreased sweating; dizziness; drowsiness; dry mouth; enlarged pupils; excitement; headache; nausea; nervousness; trouble sleeping; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; behavior changes; confusion; decreased sexual ability; diarrhea; difficulty focusing eyes; disorientation; exaggerated sense of well-being; fast or irregular heartbeat; hallucinations; loss of consciousness; loss of coordination; memory loss; mental or mood changes; severe or persistent trouble sleeping; speech changes; taste changes; trouble urinating; unusual tiredness or weakness; vision changes; vomiting.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include disorientation; excessive thirst or excitability; fever; hot, dry skin; seizures; severe dry mouth; severe or persistent blurred vision, headache, dizziness, nausea, or vomiting; trouble breathing or swallowing.

Proper storage of Hyoscyamine Elixir:

Store Hyoscyamine Elixir at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Hyoscyamine Elixir out of the reach of children and away from pets.

General information:

  • If you have any questions about Hyoscyamine Elixir, please talk with your doctor, pharmacist, or other health care provider.
  • Hyoscyamine Elixir is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Hyoscyamine Elixir. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.


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