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Alrex Drops is used for:

Providing temporary relief of itching, redness, swelling, and irritation of the eye caused by seasonal allergies.

Loteprednol is an ophthalmic corticosteroid. It decreases inflammation (eg, redness, swelling, warmth, pain) of the eye.

Do NOT use Alrex Drops if:

• you are allergic to any ingredient in Alrex Drops
• you have a bacterial, viral, or mycobacterial infection of the eye

Contact your doctor or health care provider right away if any of these apply to you.

Before using Alrex Drops:

Some medical conditions may interact with Alrex Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you wear soft contact lenses
• if you have cataract surgery, diabetes, eye discharge, thinning of the cornea or sclera, or glaucoma
• if you have a history of herpes simplex of the eye

Some MEDICINES MAY INTERACT with Alrex Drops. However, no specific interactions with Alrex Drops are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Alrex Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Alrex Drops:

Use Alrex Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Alrex Drops is for use in the eye only. Avoid contact with other mucous membranes.
• Shake well before using.
• To use Alrex Drops, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them. To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed.
• If you miss a dose of Alrex Drops, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Alrex Drops.

Important safety information:

• Alrex Drops may cause blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Alrex Drops. Using Alrex Drops alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
• Alrex Drops contains benzalkonium chloride, a preservative that may be absorbed by soft contact lenses; wait at least 10 minutes following use of Alrex Drops before reinserting lenses.
• Do not wear contact lenses if your eyes are red.
• If Alrex Drops is used for more than 10 days, your eyes will need to be re-evaluated by your eye care provider.
• If symptoms do not improve after 2 days, or pain, redness, itching, or inflammation worsens, talk with your eye doctor.
• Use Alrex Drops with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.
• PREGNANCY and BREAST-FEEDING: It is unknown if Alrex Drops can cause harm to the fetus. If you become pregnant while taking Alrex Drops, discuss with your doctor the benefits and risks of using Alrex Drops during pregnancy. It is unknown if Alrex Drops is excreted in breast milk. If you are or will be breast-feeding while you are using Alrex Drops, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Alrex Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; discharge; dry eyes; eye redness; eye/eyelid swelling; foreign body sensation; headache; increased tearing; itching; runny nose; sensitivity to light; sore throat; stinging when placed in the eye.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; continued or worsening itching; delayed healing after surgery; eye pain; severe redness or swelling.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Store Alrex Drops in an upright position between 59 and 77 degrees F (15 and 25 degrees C). Do not freeze. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Alrex Drops out of the reach of children and away from pets.

General information:

• If you have any questions about Alrex Drops, please talk with your doctor, pharmacist, or other health care provider.
• Alrex Drops is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Alrex Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.